Guide to Fredericktown Area Wineries
Fredericktown is a practical place to start a winery trip in southeast Missouri. The city is in Madison County, and its location puts us within reach of one winery tied directly to Fredericktown plus several winery destinations in nearby Marquand, Farmington, and Ste. Genevieve. That setup makes it easy to plan a shorter outing close to town or a longer day that covers a few different stops.

Vance Vineyards & Winery
Vance Vineyards & Winery is the Fredericktown name on this list, so it carries the strongest local connection. Its tasting room is located at Beaver Valley Golf Course, and the winery’s official site currently notes that it is open for private parties only. That means this stop fits best for planned visits rather than a casual same-day tasting.
Even with limited public access, Vance still belongs in a guide to Fredericktown Missouri wineries because it gives the city a clear place in the local wine scene. A regional winery listing describes it as a family-owned operation with fourteen acres under cultivation, which adds some weight to its role as the hometown winery in this group.
Durso Hills Winery & Victoria Vineyards
Durso Hills Winery & Victoria Vineyards is one of the easiest nearby options from Fredericktown. The winery is in Marquand at 4994 Highway A, and its official site describes a large barn-style facility in the rolling hills near Cherokee Pass. That setting gives the trip a stronger destination feel than a quick stop at a small tasting counter.
This winery also works well for travelers who want more than a tasting. The property includes a bistro, and state tourism listings show regular public hours from Thursday through Sunday. That combination makes Durso Hills a strong pick for a relaxed lunch or dinner outing from Fredericktown, especially when the goal is to spend a few hours in one place instead of moving quickly from stop to stop.
Charleville Brewery & Winery
Charleville Brewery & Winery brings a broader food-and-drink experience into the mix. The winery is located at 16937 Boyd Road in western Ste. Genevieve County, and its official site says it has been crafting wine and beer there since June 2003. The property includes a tasting room and patio with views above the Saline Creek Valley, which helps it stand out as a longer-stay stop rather than a quick pour-and-go visit.
Charleville fits nicely into a Fredericktown winery guide because one property covers several kinds of outings. The site includes indoor and outdoor seating, a kitchen, an overnight log cabin, and an event venue, while current hours listed by the local tourism office run from Wednesday through Sunday. For anyone building a full-day trip toward Ste. Genevieve, Charleville gives us a winery stop that can also double as a meal stop or part of a weekend stay.
Weingarten Vineyard
Weingarten Vineyard remains one of the more established winery outings within driving range of Fredericktown. The vineyard is located at 12323 Rottler Lane in Ste. Genevieve, and its official site lists public hours on Friday, Saturday, Sunday, and the first Thursday of each month. The property also runs a kitchen, which adds another reason to spend more time there instead of treating it as a brief tasting stop.
From Fredericktown, Weingarten works best as part of a slower day in Ste. Genevieve. The schedule, food service, and winery setting all support a more settled visit, so it makes sense for afternoons when we want one of the winery stops to feel like the center of the day rather than a short stop between towns.
Twin Oaks Winery
Twin Oaks Event Center, Winery & Brewhouse in Farmington adds another easy option from Fredericktown. Its official site describes a property built around handcrafted wines, small-batch craft beer, and a full bar, which gives the experience a wider social appeal than a traditional tasting room alone. The same site also notes that public hours are focused on Friday through Sunday.
Twin Oaks is a useful stop when the group wants a winery setting with more room for events and casual gatherings. Because the property is built as an event center as well as a winery and brewhouse, it suits birthdays, weekend meetups, and laid-back afternoons that call for a larger venue.
How to Plan a Winery Day from Fredericktown
The simplest way to plan a winery day from Fredericktown is to think in two directions. Vance Vineyards keeps us tied to Fredericktown when private arrangements are available, while Durso Hills gives us the closest straightforward public winery outing. A longer drive opens up Farmington and Ste. Genevieve, where Twin Oaks, Weingarten, and Charleville offer the strongest mix of current public access, food service, and time-on-site appeal.
Fredericktown works well in this role because it does not need to be a major wine destination on its own to be useful. It serves as a solid home base for exploring several southeast Missouri wineries without packing the day too tightly. With one winery tied directly to town and several established options nearby, Fredericktown gives us a clear starting point for a weekend built around tasting rooms, country drives, and a few well-chosen stops.


